Stars React To Their Golden Globe Nominations

The 70th Annual Golden Globe nominations were announced this morning from Hollywood, recognizing the best in film and television. From Nicole Kidman to Tim Burton, read on below for the stars' reactions to their big honors!

Leonardo DiCaprio, nominated for Best Supporting Actor, Django Unchained:
"I'm truly honored to be nominated by the Hollywood Foreign Press Association today. Django Unchained was a remarkable experience and I consider myself lucky to work with Quentin and the entire cast on the film. I'm particularly proud to be named alongside my fellow Django nominees."

Daniel Day-Lewis, nominated for Best Actor - Drama, Lincoln:
"Just so happy to have a really good reason to stop Christmas shopping for a day. Opening a bottle immediately to celebrate my Golden Globe nomination for Homeland. I'm thrilled that Claire and Mandy were also nominated for their performances, and look forward to celebrating with the whole cast in Los Angeles in January. Thank you HFPA!"

Taylor Swift, nominated for Best Original Song, Safe & Sound for The Hunger Games:
"What an amazing and unexpected present! I'm blown away by my first-ever Golden Globe nomination, and so honored to be nominated with T Bone Burnett and The Civil Wars. Writing music for The Hunger Games was a labor of love -- I was a fan of the stories and the characters, and we all wanted the music to have an authenticity that matched the tone of the movie and the emotions expressed in the book. This is a huge honor, and I'm really excited and so flattered. THANK YOU from the bottom of my heart to the Hollywood Foreign Press Association!"

Nicole Kidman, nominated for Best Supporting Actress, The Paperboy and Best Actress Mini-Series or TV Movie, Hemingway & Gellhorn:
"As an actor you look for roles that are rich, complicated, and that stretch you and this year I was blessed to find two. To have the chance to play them was a gift in itself and to then be acknowledged this way is icing on the cake. Thank you to the Hollywood Foreign Press!"

Related: 2013 Golden Globes -- And the Nominees Are ...

Tim Burton, nominated for Best Animated Feature, Frankenweenie:
"I'm thrilled to be recognized by the HFPA. Frankenweenie is a very personal project for me and the nomination goes as much to the animators who labored frame by frame to bring this film to life."

Clive Owen, nominated for Best Actor, Mini-Series or TV Movie, Hemingway & Gellhorn:
"I'd like to say a big thank you to The Hollywood Foreign Press. I am really thrilled as this recognition is for a piece of work I'm very proud of and had such a good time on."

Amy Adams, nominated for Best Supporting Actress, The Master:
"Thank you to the Hollywood Foreign Press for this nomination. I’m so appreciative to have been part of Paul Thomas Anderson’s extraordinary film and to have had the opportunity to star alongside such respected actors as Philip Seymour Hoffman and Joaquin Phoenix who were nothing short of brilliant in their performances."

Bradley Cooper, nominated for Best Actor, Silver Linings Playbook:
"To see this film recognized by the HFPA is huge for us. And for me, personally, to be in a room with Bill Murray, Daniel Day-Lewis? Forget about it!," Cooper tells The Hollywood Reporter. "We released the film in limited theaters, so it's all been about word of mouth in a very positive way. These nominations bode well for more people being able to see it. At all these screenings and Q&As, so many people say they are very affected by it; that the family feels real and relatable…that's all [director] David O. Russell. That's the film he set out to make. A movie about real people."

Ewan McGregor, nominated for Best Actor, Salmon Fishing in the Yemen:
"Thank you to the Hollywood Foreign Press for this nomination. It's wonderful that our movie left its mark. Emily Blunt is such a talent and a joy to work with, and I'm so happy the HFPA recognized her performance, as well as our film. I look forward to the Golden Globes, as they are always fun and send my congratulations to all those who believed and participated in Lasse's vision."

Emily Blunt, nominated for Best Actress, Salmon Fishing in the Yemen:
"I'm so incredibly thankful to the Hollywood Foreign Press for recognizing our little movie that could. Ewan and the entire cast and crew could not be more deserving of this honor, and I'm thrilled that I'm able to share this moment among such a fantastic group of nominees."

Jack Black, nominated for Best Actor - Comedy or Musical, Bernie:
"Ok...I'm only doing Richard Linklater movies from now on. I'm so proud of our little engine that could. Thank you HFPA!"

Hayden Panettiere, nominated for Best Supporting Actress, Nashville:
"I'm the epitome of surprise and shocked!," Panettiere tells The Hollywood Reporter. "I didn't know whether to ball hysterically or jump up and down on the bed so I decided to do both. I feel like I'm going through the same struggles as Juliette: she wants to be respected in her craft, she knows how people perceive her and what they think she's capable of but she knows capable of more and I feel like I've been fighting the same battle and it's paid off. I'm so flattered and humbled."

Glenn Close, nominated for Best Actress - Drama, Damages:
"Damages was one of the greatest adventures of my career. I am deeply grateful to The Hollywood Foreign Press for their recognition of my work in our final season. I represent our entire Damages team in thanking them for their support over the past five years. Patty Hewes was the inspiration of a brilliant team of writers, honed by her interactions with a remarkable roster of guest stars. I couldn’t have had a better partner in the exquisite Rose Byrne. The relationship of Patty Hewes and Ellen Parsons is unique storytelling. Their journey resulted in what I think is a great modern American tragedy that will stand the test of time."

Max Greenfield, nominated for Best Supporting Actor, New Girl:
"I got the phone call at 5:30 in the morning, and now the house is awake -- including my daughter, who is never up this early. She has demanded Dora The Explorer, so that is happening," Greenfield tells The Hollywood Reporter. "This is amazing, though. There was an email going around when it happened with my manager and my agent and a bunch of people, and my only response was 'Does this mean I'm as good of an actor as [fellow nominee] Ed Harris?' I can literally tell you what movie theater and where exactly I was sitting when I saw Pollock."

Lena Dunham, nominated for Best Actress - Comedy or Musical and Best Series - Musical or Comedy, Girls:
"This is an incredible honor and the most wonderful ending to an amazing year. Thank you to the Hollywood Foreign Press. I'm thrilled to share this with our amazing cast and crew."

Rachel Weisz, nominated for Best Actress - Drama, Deep Blue Sea:
"I am deeply grateful for this nomination, and in particular, for the HFPA's recognition of the hard work and passion that Terence Davies brought to this wonderful British indie. I am thrilled that this nomination might allow his beautiful work to reach a larger audience."

Alan Arkin, nominated for Best Supporting Actor, Argo:
"I am deeply grateful for this honor and particularly moved in being in the company of Christoph Waltz, Leonardo DiCaprio, Philip Seymour Hoffman, and Tommy Lee Jones who I deeply admire. I am also thrilled that Ben is getting the attention he so much deserves, as is Argo."

Matt LeBlanc, nominated for Best Actor - Comedy or Musical, Best Series - Comedy or Musical, Episodes:
"It's an incredible honor to be nominated again for a show that I am so proud to be a part of. And I am thrilled that the show has been recognized as well because everyone involved works so hard. Thank you Hollywood Foreign Press."

Quentin Tarantino, nominated for Best Picture - Drama, Best Director and Best Screenplay, Django Unchained:
"It's very gratifying to get this many nominations from the HFPA for a film I worked so hard on and am so passionate about. I look forward to having fun at the Golden Globes with my cast mates and fellow nominees."

Steve Buscemi, nominated for Best Actor - Drama, Boardwalk Empire:
"I'm so grateful to be able to play Nucky, it never gets old."

Jeff Daniels, nominated for Best Actor, Drama and Best Series, Drama, The Newsroom:
"To me, being honored with a Golden Globe Nomination means even more because it's for THE NEWSROOM."

Julia Louis-Dreyfus, nominated for Best Actress - Comedy or Musical, Veep:
"The reason that I do this job is to serve, not to receive accolades and trophies. That said, I'm freakin' stoked. God bless America and the Hollywood Foreign Press, specifically."

Don Cheadle, nominated for Best Actor - Comedy or Musical, House of Lies:
"I'm over the moon for the nom. This is a great show and a great cast and this is a recognition of all of us... But mostly me."

Mandy Patinkin, nominated for Best Supporting Actress, Homeland:
"I am thrilled to be a part of this company. Working on HOMELAND has been one of the joys of my life. We have such gifted writers - I have to pinch myself every day that I get to be a part of this company. Still - the real big news we are all waiting for is Claire's baby. When I get that call, the fireworks will really start."

Kathryn Bigelow, nominated for Best Director and Best Picture - Drama, Zero Dark Thirty:
"It's an honor, sincerely, and very humbling to be singled out this way by the HFPA. We're grateful, and encouraged by their support, especially since our film has such a diverse, international cast, and as the HFPA represent so many countries across the globe. And a big congratulations to the amazing Jessica Chastain and my producing partner and screenwriter Mark Boal."

John Hawkes, nominated for Best Actor - Drama, The Sessions:
"I'm so honored by these nominations and excited that the film is receiving this recognition."

Homeland co-creator Howard Gordon, nominated for Best Drama Series:
"It's a been a great year for television and to be recognized by the HFPA in the company of such extraordinary nominees is an incredible thrill. We're grateful to all the other shows on television for raising the standards each year and to everyone involved with Homeland – from the cast and crew to Showtime and Fox 21 for their hard work, creativity and support."

Director Rich Moore, nominated for Best Animated Feature, Wreck-It Ralph:
"Wreck-It Ralph was a labor of love for our entire team at Walt Disney Animation. We are so proud of the hard work that went into making this film, and to see it be recognized with a nomination from the Hollywood Foreign Press Association is truly an honor for all of us."

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Dozens sue pharmacy, but compensation uncertain

NASHVILLE, Tenn. (AP) — Dennis O'Brien rubs his head as he details ailments triggered by the fungal meningitis he developed after a series of steroid shots in his neck: nausea, vomiting, dizziness, drowsiness, blurred vision, exhaustion and trouble with his speech and attention.

He estimates the disease has cost him and his wife thousands of dollars in out-of-pocket expenses and her lost wages, including time spent on 6-hour round trip weekly visits to the hospital. They've filed a lawsuit seeking $4 million in damages from the Massachusetts pharmacy that supplied the steroid injections, but it could take years for them to get any money back and they may never get enough to cover their expenses. The same is true for dozens of others who have sued the New England Compounding Center.

"I don't have a life anymore. My life is a meningitis life," the 59-year-old former school teacher said, adding that he's grateful he survived.

His is one of at least 50 federal lawsuits in nine states that have been filed against NECC, and more are being filed in state courts every day. More than 500 people have gotten sick after receiving injections prepared by the pharmacy.

The lawsuits allege that NECC negligently produced a defective and dangerous product and seek millions to repay families for the death of spouses, physically painful recoveries, lost wages and mental and emotional suffering. Thirty-seven people have died in the outbreak.

"The truth is the chance of recovering damages from NECC is extremely low," said John Day, a Nashville attorney who represents several patients who have been sickened by fungal meningitis.

To streamline the process, attorneys on both sides are asking to have a single judge preside over the pretrial and discovery phases for all of the federal lawsuits.

This approach, called multidistrict litigation, would prevent inconsistent pretrial rulings and conserve resources of all parties. But unlike a class-action case, those lawsuits would eventually be returned to judges in their original district for trial, according to Brian Fitzpatrick, a law professor at Vanderbilt University Law School in Nashville.

Even with this approach, Fitzpatrick noted that federal litigation is very slow, and gathering all the evidence, records and depositions during the discovery phase could take months or years.

"Most of the time what happens is once they are consolidated for pretrial proceedings, there is a settlement, a global settlement between all the lawyers and the defendants before anything is shipped back for trial," he said.

A lawyer representing NECC, Frederick H. Fern, described the consolidation process as an important step.

"A Boston venue is probably the best scenario," Fern said in an email. "That's where the parties, witnesses and documents are located, and where the acts subject to these complaints occurred."

Complicating efforts to recover damages, attorneys for the patients said, NECC is a small private company that has now recalled all its products and laid off its workers. The company's pharmacy licenses have been surrendered, and it's unclear whether NECC had adequate liability insurance.

Fern said NECC has insurance, but they were still determining what the policy covers.

But Day says, "It's clear to me that at the end of the day, NECC is not going to have sufficient assets to compensate any of these people, not even 1 percent."

As a result, many attorneys are seeking compensation from other parties. Among the additional defendants named in lawsuits are NECC pharmacist and co-founder Barry Cadden; co-founder Greg Conigliaro; sister company Ameridose and its marketing and support arm, Medical Sales Management.

Founded in 2006 by Cadden and Conigliaro, Ameridose would eventually report annual revenue of $100 million. An NECC spokesman didn't respond to a request for the pharmacy's revenue.

While Federal Drug Administration regulators have also found contamination issues at Westborough, Mass.-based Ameridose, the FDA has said it has not connected Ameridose drugs to infection or illness.

Under tort law, a lawsuit has to prove a defendant has a potential liability, which in this case could be anyone involved in the medical procedure. However, any such suit could take years and ultimately may not be successful.

"I would not be surprised if doctors, hospitals, people that actually injected the drugs, the people that bought the drugs from the compounding company, many of those people will also be sued," said Fitzpatrick.

Plaintiffs' attorneys said they're considering that option but want more information on the relationships between the compounding pharmacy and the hundreds of hospitals and clinics that received its products.

Day, the attorney in Tennessee, said the clinics and doctors that purchase their drugs from compounding pharmacies or manufacturers could be held liable for negligence because they are in a better position to determine the safety of the medicine than the patients.

"Did they use due care in determining from whom to buy these drugs?" Day said.

Terry Dawes, a Michigan attorney who has filed at least 10 federal lawsuits in the case, said in traditional product liability cases, a pharmaceutical distributor could be liable.

"We are looking at any conceivable sources of recovery for our clients including pharmaceutical supply places that may have dealt with this company in the past," he said.

Ten years ago, seven fungal meningitis illnesses and deaths were linked to injectable steroid from a South Carolina compounding pharmacy. That resulted in fewer than a dozen lawsuits, a scale much smaller than the litigations mounting up against NECC.

Two companies that insured the South Carolina pharmacy and its operators tried unsuccessfully to deny payouts. An appellate court ruled against their argument that the pharmacy willfully violated state regulations by making multiple vials of the drug without specific prescriptions, but the opinion was unpublished and doesn't set a precedent for the current litigation.

The lawsuits represent a way for patients and their families recover expenses, but also to hold the pharmacy and others accountable for the incalculable emotional and physical toll of the disease.

A binder of snapshots shows what life is like in the O'Briens' rural Fentress County, Tenn., home: Dennis hooked up to an IV, Dennis in an antibiotics stupor, bruises on his body from injections and blood tests. He's had three spinal taps. His 11-day stay in the hospital cost over $100,000, which was covered by health insurance.

His wife said she sometimes quietly checks at night to see whether her husband of 35 years is still breathing.

"In my mind, I thought we were going to fight this and get over it. But we are not ever going to get over it," said Kaye O'Brien.

Marjorie Norwood, a 59-year-old grandmother of three who lives in Ethridge, Tenn., has spent just shy of two months total in the hospital in Nashville battling fungal meningitis after receiving a steroid injection in her back. She was allowed to come home for almost a week around Thanksgiving, but was readmitted after her symptoms worsened.

Family members are still dealing with much uncertainty about her recovery, but they have not filed a lawsuit, said their attorney Mark Chalos. He said Norwood will likely be sent to a rehabilitation facility after her second stay in the hospital rather than return home again.

Marjorie Norwood's husband, an autoworker, has taken time off work to care for her and they depend on his income and insurance.

"It doesn't just change her life, it changes everyone else's life around her because we care about her and want her to be happy and well and have everything that she needs," said her daughter, Melanie Norwood.

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Wall Street little changed as caution tempers data

NEW YORK (Reuters) - Stocks opened little changed on Thursday after data showed first time claims for jobless benefits fell sharply last week, but investors were cautious about making aggressive bets in the midst of ongoing "fiscal cliff" negotiations.

Shares of Best Buy Co surged almost 18 percent after a report that the company's founder is expected to make a fully financed offer to buy the consumer electronics retailer by the end of the week. Best Buy was up 17.9 percent at $14.36, making it the biggest gainer on the S&P 500.

Other economic data on Thursday showed retail sales rose in November after an October decline, brightening the picture for consumer spending.

Still, equities gains were constrained as the set of tax hikes and spending cuts that are set to come into effect in the new year remained at the forefront of investors' minds. Negotiators on Wednesday warned the showdown over reaching a deal on the so-called fiscal cliff could drag on past Christmas.

"With the suggestion that they're not any closer than they were a few days ago, we're really just in a market that's trying to figure out what the next catalyst might be," said Kate Warne, investment strategist at Edward Jones in St Louis.

"I think we need to see either an actual plan or signs that they've worked out a way to be sure they don't end up disagreeing at the last minute. Either of those would be positive, but so far we're not seeing anything that suggests either one."

The Federal Reserve on Wednesday announced a fresh bout of stimulus for the U.S. economy, but markets focused on comments from Chairman Ben Bernanke, who reiterated that monetary policy would not be enough to offset going over the fiscal cliff.

Investors are worried that doing so could send the economy back into recession, though most expect a deal will be struck eventually.

The Dow Jones industrial average <.dji> inched up 2.11 points, or 0.02 percent, at 13,247.56. The Standard & Poor's 500 Index <.spx> edged down 0.56 point, or 0.04 percent, at 1,427.92. The Nasdaq Composite Index <.ixic> eased 2.51 points, or 0.08 percent, to 3,011.31.

If the S&P 500 ends the session lower, it would break a six-day winning streak. Some of those days saw only slight gains on lower volume.

In the European Union, finance ministers reached a deal to make the European Central Bank the bloc's top banking supervisor. The move could boost confidence in leaders' ability to tackle the region's sovereign debt crisis.

Initial claims for state unemployment benefits dropped 29,000 to a seasonally adjusted 343,000, pointing to healing in the labor market.

Separate reports released at the same time showed producer prices fell more than expected in November, while retail sales rebounded though not by as much as expected.

CVS Caremark Corp gained 3.4 percent to $49.16 after it said it expects higher earnings next year.

(Editing by Kenneth Barry)

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IMF loan to Egypt delayed as crisis deepens

CAIRO (Reuters) - A vital $4.8 billion International Monetary Fund loan to Egypt will be delayed until next month, its finance minister said on Tuesday, intensifying the political crisis gripping the Arab world's most populous nation.

As rival factions gathered in Cairo and Alexandria for a new round of demonstrations, Finance Minister Mumtaz al-Said said the delay in the loan agreement was intended to allow time to explain a heavily criticised package of economic austerity measures to the Egyptian people.

The announcement came after President Mohamed Mursi on Monday backed down on planned tax increases, seen as key for the loan to go ahead. Opposition groups had greeted the tax package, which had included duties on alcoholic drinks, cigarettes and a range of goods and services, with furious criticism.

"Of course the delay will have some economic impact, but we are discussing necessary measures (to address that) during the coming period," the minister told Reuters, adding: "I am optimistic ... everything will be well, God willing."

Prime Minister Hisham Kandil said Egypt had requested that the loan be delayed by a month.

"The challenges are economic not political and must be dealt with aside from politics," he told a news conference.

Kandil said the reforms would not hurt the poor. Bread sugar and rice would not be touched, but cigarettes and cooking oil would go up and fines would be imposed for public littering. In a bid to rebuild consensus, he said there would be a national dialogue about the economic program next week.

In Washington, the IMF said Egypt had asked for the loan to be postponed "in light of the unfolding developments on the ground". The Fund stood ready to consult with Egypt on resuming discussions on the stand-by loan, a spokeswoman said.

GUNMEN OPEN FIRE

On the streets of the capital, tensions ran high after nine people were hurt when gunmen fired at protesters camping in Tahrir Square, according to witnesses and Egyptian media.

The opposition has called for a major demonstration it hopes will force Mursi to postpone a referendum on a new constitution.

Outside the presidential palace, dozens of protesters succeeded in pushing down two giant concrete blocks forming a small part of a wall blocking access to the site.

Thousands of flag-waving Islamist Mursi supporters, who want the vote to go ahead as planned on Saturday, assembled at a nearby mosque, setting the stage for further street confrontations in a crisis that has divided the nation of 83 million.

In Egypt's second city of Alexandria, thousands of rival demonstrators gathered at separate venues. Mursi's backers chanted: "The people want implementation of Islamic law," while his opponents shouted: "The people want to bring down the regime."

The upheaval following the fall of Hosni Mubarak last year is causing concern in the West, in particular the United States, which has given Cairo billions of dollars in military and other aid since Egypt made peace with Israel in 1979.

The turmoil has also placed a big strain on the economy, sending foreign currency reserves down to about $15 billion, less than half what they were before the revolt two years ago as the government has sought to defend the pound.

"Given the current policy environment, it's hardly a surprise that there's been a delay, but it is imperative that the delay is brief," said Simon Williams, HSBC economist in Dubai. "Egypt urgently needs that IMF accord, both for the funding it brings and the policy anchor it affords."

The IMF deal had been seen as giving a seal of approval to investors and donors about the government's economic plans, vital for drawing more cash into the economy to ease a crushing budget deficit and stave off a balance of payments crisis.

MASKED ATTACKERS

In central Cairo, police cars surrounded Tahrir Square in central Cairo, the first time they had appeared in the area since November 23, shortly after a decree by Mursi awarding himself sweeping temporary powers that touched off widespread protests.

The attackers, some masked, also threw petrol bombs that started a small fire, witnesses said.

"The masked men came suddenly and attacked the protesters in Tahrir. The attack was meant to deter us and prevent us from protesting today. We oppose these terror tactics and will stage the biggest protest possible today," said John Gerges, a Christian Egyptian who described himself as a socialist.

The latest bout of unrest has so far claimed seven lives in clashes between the Islamist Muslim Brotherhood and opponents who are also gathering outside Mursi's presidential palace.

The elite Republican Guard which protects the palace has yet to use force to keep protesters away from the graffiti-daubed building, now ringed with tanks, barbed wire and concrete barricades.

The army has told all sides to resolve their differences through dialogue, saying it would not allow Egypt to enter a "dark tunnel". For the period of the referendum, the army has been granted police powers by Mursi, allowing it to arrest civilians.

The army has portrayed itself as the guarantor of the nation's security, but so far it has shown no appetite for a return to the bruising front-line political role it played after the fall of Mubarak, which severely damaged its standing.

OPPOSITION MARCHES

Leftists, liberals and other opposition groups called for marches say the hastily arranged constitutional referendum is polarizing the country and could put it in a religious straightjacket.

Mohamed ElBaradei, a prominent opposition leader and Nobel prize winner, said the referendum should be postponed for a couple of months due to the chaotic situation.

"This revolution was not staged to replace one dictator with another," he said in an interview with CNN.

Opposition leaders want the referendum to be delayed and hope they can get sufficiently large numbers of protesters on the streets to change Mursi's mind.

Islamists, who dominated the body that drew up the constitution, have urged their followers to turn out to show support for the president and for a referendum they feel sure of winning.

The opposition says the draft constitution fails to embrace the diversity of the population, a tenth of which is Christian, and invites Muslim clerics to influence lawmaking.

(Writing by Giles Elgood; Editing by Peter Graff and Will Waterman)

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Fergie Dresses Up as 'Naughty Santa' For Josh Duhamel

Fergie revealed how she and husband Josh Duhamel keep things hot during the holiday season -- and it involves a sexy costume.

"One day every holiday season, he comes home and there's a naughty Mrs. Claus," the Black Eyed Peas front woman revealed to Ellen DeGeneres. "It depends how good he's being!"

A playful Fergie, 37, added, "It's a surprise. It's naughty and nice at the same time. It's super cute and fun."

Ellen also checked in on the thong she gifted Duhamel, 40, with the last time he was on her show. "It was too small," Fergie admitted. Ellen quipped back, "That's more information than we needed!"

RELATED: Stars In Their Best Holiday Gear

The Hollywood couple are known to send out holiday cards with a picture of themselves, but the singer confessed that they haven't mailed them out yet this year. "My husband orchestrates the whole thing and we're late this year because he's been filming a movie. He just finished Safe Haven with Julianne Hough and now he's doing You're Not You with Hilary Swank. I haven't been on the ball, so I'm waiting for him and we're going to have to do something last minute this year."

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New tests could hamper food outbreak detection

WASHINGTON (AP) — It's about to get faster and easier to diagnose food poisoning, but that progress for individual patients comes with a downside: It could hurt the nation's ability to spot and solve dangerous outbreaks.

Next-generation tests that promise to shave a few days off the time needed to tell whether E. coli, salmonella or other foodborne bacteria caused a patient's illness could reach medical laboratories as early as next year. That could allow doctors to treat sometimes deadly diseases much more quickly — an exciting development.

The problem: These new tests can't detect crucial differences between different subtypes of bacteria, as current tests can. And that fingerprint is what states and the federal government use to match sick people to a contaminated food. The older tests might be replaced by the new, more efficient ones.

"It's like a forensics lab. If somebody says a shot was fired, without the bullet you don't know where it came from," explained E. coli expert Dr. Phillip Tarr of Washington University School of Medicine in St. Louis.

The federal Centers for Disease Control and Prevention warns that losing the ability to literally take a germ's fingerprint could hamper efforts to keep food safe, and the agency is searching for solutions. According to CDC estimates, 1 in 6 Americans gets sick from foodborne illnesses each year, and 3,000 die.

"These improved tests for diagnosing patients could have the unintended consequence of reducing our ability to detect and investigate outbreaks, ultimately causing more people to become sick," said Dr. John Besser of the CDC.

That means outbreaks like the salmonella illnesses linked this fall to a variety of Trader Joe's peanut butter might not be identified that quickly — or at all.

It all comes down to what's called a bacterial culture — whether labs grow a sample of a patient's bacteria in an old-fashioned petri dish, or skip that step because the new tests don't require it.

Here's the way it works now: Someone with serious diarrhea visits the doctor, who gets a stool sample and sends it to a private testing laboratory. The lab cultures the sample, growing larger batches of any lurking bacteria to identify what's there. If disease-causing germs such as E. coli O157 or salmonella are found, they may be sent on to a public health laboratory for more sophisticated analysis to uncover their unique DNA patterns — their fingerprints.

Those fingerprints are posted to a national database, called PulseNet, that the CDC and state health officials use to look for food poisoning trends.

There are lots of garden-variety cases of salmonella every year, from runny eggs to a picnic lunch that sat out too long. But if a few people in, say, Baltimore have salmonella with the same molecular signature as some sick people in Cleveland, it's time to investigate, because scientists might be able narrow the outbreak to a particular food or company.

But culture-based testing takes time — as long as two to four days after the sample reaches the lab, which makes for a long wait if you're a sick patient.

What's in the pipeline? Tests that could detect many kinds of germs simultaneously instead of hunting one at a time — and within hours of reaching the lab — without first having to grow a culture. Those tests are expected to be approved as early as next year.

This isn't just a science debate, said Shari Shea, food safety director at the Association of Public Health Laboratories.

If you were the patient, "you'd want to know how you got sick," she said.

PulseNet has greatly improved the ability of regulators and the food industry to solve those mysteries since it was launched in the mid-1990s, helping to spot major outbreaks in ground beef, spinach, eggs and cantaloupe in recent years. Just this fall, PulseNet matched 42 different salmonella illnesses in 20 different states that were eventually traced to a variety of Trader Joe's peanut butter.

Food and Drug Administration officials who visited the plant where the peanut butter was made found salmonella contamination all over the facility, with several of the plant samples matching the fingerprint of the salmonella that made people sick. A New Mexico-based company, Sunland Inc., recalled hundreds of products that were shipped to large retailers all over the country, including Target, Safeway and other large grocery chains.

The source of those illnesses probably would have remained a mystery without the national database, since there weren't very many illnesses in any individual state.

To ensure that kind of crucial detective work isn't lost, the CDC is asking the medical community to send samples to labs to be cultured even when they perform a new, non-culture test.

But it's not clear who would pay for that extra step. Private labs only can perform the tests that a doctor orders, noted Dr. Jay M. Lieberman of Quest Diagnostics, one of the country's largest testing labs.

A few first-generation non-culture tests are already available. When private labs in Wisconsin use them, they frequently ship leftover samples to the state lab, which grows the bacteria itself. But as more private labs switch over after the next-generation rapid tests arrive, the Wisconsin State Laboratory of Hygiene will be hard-pressed to keep up with that extra work before it can do its main job — fingerprinting the bugs, said deputy director Dr. Dave Warshauer.

Stay tuned: Research is beginning to look for solutions that one day might allow rapid and in-depth looks at food poisoning causes in the same test.

"As molecular techniques evolve, you may be able to get the information you want from non-culture techniques," Lieberman said.

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Follow Mary Clare Jalonick on Twitter at http://twitter.com/mcjalonick

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Wall Street adds gains, S&P at highest since early November

NEW YORK (Reuters) - Stocks extended gains on Tuesday as an advance in tech shares sent indexes up 1 percent, helping the S&P 500 retrace all of its losses since the U.S. presidential election.

The Dow Jones industrial average <.dji> gained 123.10 points, or 0.93 percent, to 13,292.98. The Standard & Poor's 500 Index <.spx> rose 14.54 points, or 1.02 percent, to 1,433.09. The Nasdaq Composite Index <.ixic> climbed 44.30 points, or 1.48 percent, to 3,031.27.

The S&P 500 rose as high as 1,434.27, matching an intraday high seen on Nov 2.

(Reporting by Leah Schnurr; Editing by Chizu Nomiyama)

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Egypt's Mursi gives troops security role in referendum

CAIRO (Reuters) - Egypt's Islamist president has asked the army to help secure a constitutional referendum he is determined to push through despite the risk of more deadly violence between his supporters and opponents accusing him of a power grab.

Seven people were killed and hundreds wounded last week in clashes between the Islamist Muslim Brotherhood and their critics besieging Mohamed Mursi's graffiti-daubed presidential palace. Both sides plan mass rallies on Tuesday.

The elite Republican Guard has yet to use force to keep protesters away from the palace, which it ringed with tanks, barbed wire and concrete barricades after last week's violence.

Mursi, bruised by calls for his downfall, has rescinded a November 22 decree giving him wide powers but is going ahead with a referendum on Saturday on a constitution seen by his supporters as a triumph for democracy and by many liberals as a betrayal.

A decree issued by Mursi late on Sunday gives the armed forces the power to arrest civilians and refer them to prosecutors until the announcement of the results of the referendum, which the protesters want cancelled.

Despite its limited nature, the edict will revive memories of Hosni Mubarak's emergency law, also introduced as a temporary expedient, under which military or state security courts tried thousands of political dissidents and Islamist militants.

But a military source stressed that the measure introduced by a civilian government would have a short shelf-life.

"The latest law giving the armed forces the right to arrest anyone involved in illegal actions such as burning buildings or damaging public sites is to ensure security during the referendum only," the military source said.

Presidential spokesman Yasser Ali said the committee overseeing the vote had requested the army's assistance.

"The armed forces will work within a legal framework to secure the referendum and will return (to barracks) as soon as the referendum is over," Ali said.

Protests and violence have racked Egypt since Mursi decreed himself extraordinary powers he said were needed to speed up a troubled transition since Mubarak's fall 22 months ago.

The Muslim Brotherhood has voiced anger at the Interior Ministry's failure to prevent protesters setting fire to its headquarters in Cairo and 28 of its offices elsewhere.

Critics say the draft law puts Egypt in a religious straitjacket and whatever the outcome of the referendum, the crisis has polarized the country and presages more instability at a time when Mursi is trying to steady a fragile economy.

On Monday, he suspended planned tax increases only hours after the measures had been formally decreed, casting doubts on the government's ability to push through tough economic reforms that form part of a proposed $4.8 billion IMF loan agreement.

"VIOLENT CONFRONTATION"

Rejecting the referendum plan, opposition groups have called for mass protests on Tuesday, saying Mursi's eagerness to push the constitution through could lead to "violent confrontation".

Islamists have urged their followers to turn out "in millions" the same day in a show of support for the president and for a referendum they feel sure of winning with their loyal base and perhaps with the votes of Egyptians weary of turmoil.

The opposition National Salvation Front, led by liberals such as Mohamed ElBaradei and Amr Moussa, as well as leftist firebrand Hamdeen Sabahy, has yet to call directly for a boycott of the referendum or to urge their supporters to vote "no".

Instead it is contesting the legitimacy of the vote and of the whole process by which the constitution was drafted in an Islamist-led assembly from which their representatives withdrew.

The opposition says the document fails to embrace the diversity of 83 million Egyptians, a tenth of whom are Christians, and invites Muslim clerics to influence lawmaking.

But debate over the details has largely given way to noisy street protests and megaphone politics, keeping Egypt off balance and ill-equipped to deal with a looming economic crisis.

"Inevitability of referendum deepens divisions," was the headline in Al-Gomhuriya newspaper on Monday. Al Ahram daily wrote: "Political forces split over referendum and new decree."

Mursi issued another decree on Saturday to supersede his November 22 measure putting his own decisions beyond legal challenge until a new constitution and parliament are in place.

While he gave up extra powers as a sop to his opponents, the decisions already taken under them, such as the dismissal of a prosecutor-general appointed by Mubarak, remain intact.

"UNWELCOME" CHOICE

Lamia Kamel, a spokeswoman for former Arab League chief Moussa, said the opposition factions were still discussing whether to boycott the referendum or call for a "no" vote.

"Both paths are unwelcome because they really don't want the referendum at all," she said, but predicted a clearer opposition line if the plebiscite went ahead as planned.

A spokeswoman for ElBaradei, former head of the U.N. nuclear watchdog, said: "We do not acknowledge the referendum. The aim is to change the decision and postpone it."

Mahmoud Ghozlan, the Muslim Brotherhood's spokesman, said the opposition could stage protests, but should keep the peace.

"They are free to boycott, participate or say no, they can do what they want. The important thing is that it remains in a peaceful context to preserve the country's safety and security."

The army stepped into the conflict on Saturday, telling all sides to resolve their disputes via dialogue and warning that it would not allow Egypt to enter a "dark tunnel".

A military source said the declaration read on state media did not herald a move by the army to retake control of Egypt, which it relinquished in June after managing the transition from Mubarak's 30 years of military-backed one-man rule.

The draft constitution sets up a national defense council, in which generals will form a majority, and gives civilians some scrutiny over the army - although not enough for critics.

In August Mursi stripped the generals of sweeping powers they had grabbed when he was elected two months earlier, but has since repeatedly paid tribute to the military in public.

So far the army and police have taken a relatively passive role in the protests roiling the most populous Arab nation.

(Additional reporting by Edmund Blair and Yasmine Saleh; editing by Philippa Fletcher)

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Hug It Out: Public Charter and District Schools Given $25 Million to Get Along

If you need a loan, ask Bill and Melinda Gates. Or better yet, ask one of the seven cities that are splitting a new $ 25 million grant courtesy of the couple’s philanthropic foundation.

The funds are going to promote cross collaboration between charter and district schools, which have previously operated in a strict and contentious independence from one another.

The foundation announced the award this week, and the cities benefiting are Boston, Denver, Hartford (CT), New Orleans, New York City, Philadelphia and Spring Branch (TX).

How did they get so lucky? They’re among a group of 16 communities that signed the Gates-sponsored “District-Charter Collaboration Compacts” pledging for an open-source collaboration between public charter and district public schools.

Communication between these two models is unusual to say the least; they’ve had a long and illustrious history of battling each other over tax dollars, students and even building space.

But when charter schools first opened 20 years ago, their original purpose was to create an experimental educational space which would then share its best methods with public district schools. Instead, the two grew into rivals and critics of each are vehemently opposed to the other.

Among the complaints, charter schools are seen as selfishly siphoning off the most motivated students from the district while upholding a rich-poor educational divide and failing to live up to the promise of a better education. Others say its district schools that are the issue for their unionized teacher complacency and a consistent inability to keep a large margin of students from falling through the cracks.

In truth, neither system is a slam-dunk, and both are experiencing closures nationwide due to underperformance.

The goal of the District-Charter Collaboration Compacts is to restore the original relationship of the two camps, effectively establishing a regular protocol of sharing their best practices, innovations and resources.

Don Shalvey, the deputy director at teh Gates Foundation told The New York Times, “It took Microsoft and Apple 10 years to learn to talk. So it’s not surprising that it took a little bit longer for charters and other public schools. It’s pretty clear there is more common ground than battleground.”

But what will this grand collaboration yield? If all goes according to plan, students from both camps will benefit from new teacher effectiveness practices, college-ready tools and supports, and innovative instructional delivery systems.

According to the Gates Foundation, only one-third of students meet the criteria of college ready by the time they graduate. And most of the kids who don’t are often minority students from lower income areas. By creating collaborative aims with charter and district, kids from all over can have access to a wider swath of teaching frameworks and curriculums. 

Related Stories on TakePart:

• Public Dollars for Private Schools? Voices from the Voucher Debate

• School Vouchers: The Debate Heats Up Across the U.S.

• Howard Fuller: One of the Most Powerful Educators in America

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A Bay Area native, Andri Antoniades previously worked as a fashion industry journalist and medical writer.  In addition to reporting the weekend news on TakePart, she volunteers as a webeditor for locally-based nonprofits and works as a freelance feature writer for TimeOutLA.com. Email Andri | @andritweets | TakePart.com

Linux/Open Source News Headlines – Yahoo! News

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Tom Brady: My Daughter Will Be An Athlete

After news hit that Gisele Bundchen gave birth to daughter Vivian Lake this past week, doting dad Tom Brady gushed over his new bundle of joy.

"It feels good,’’ Brady, 35, told the Boston Herald of the latest addition to his family. "Whatever we would have had, I would have been happy. We've got two beautiful boys, now a girl. It's great."

This is the third child for Brady, who has a 2-year-old son, Benjamin, with his supermodel wife, and a 5-year-old son, John, with actress Bridget Moynahan. Ben turned three on Saturday.

The New England Patriots QB assured the local newspaper that his wife and daughter were happy and healthy, adding that his little girl is "going to be an athlete."

Bundchen, 32, confirmed on her Facebook page Friday that she and Brady welcomed their second child together on Wednesday night. "We feel so lucky to have been able to experience the miracle of birth once again and are forever grateful for the opportunity to be the parents of another little angel," she said of her newborn.

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